Patient-centered medicine in AD was highlighted last month by the JEADV clinical practice patient page summarizing the International Meeting of the Eczema Foundation which took place in Malta from 15 to 18 June 2022. It gathered 150 attendants from 25 countries and 5 continents. Patients, doctors, nurses and caregivers discussed and shared their experiences. This meeting addressed the multiple facets (medical, psychological, educational, cultural, etc.) of AD and several short interviews were recorded.
Of note, a milestone paper was published last month by a team of Southampton (UK) in Nature communications investigating the molecular crosstalk underpinning tolerance versus inflammation in atopic dermatitis using a human in vivo allergen challenge study exposing atopic dermatitis patients to house dust mite. This study shows nicely that reactivity to house dust mite is associated with high basal levels of TNF-expressing cutaneous Th17 T cells, and that antioxidant defenses, so far quite neglected in the pathophysiology of AD, protect against allergen-induced inflammation.