Eczema herpeticum after topical JAK inhibition:Eczema Herpeticum Following Topical Ruxolitinib Use: A Report of Two CasesZhang K et al. Annals of Allergy, Asthma & Immunology. 2026.➜ DOI: 10.1016/j.anai.2026.06.016Why it matters:Eczema herpeticum is one of the most clinically important infectious complications of AD. These two cases are noteworthy because they occurred following treatment with topical ruxolitinib, reminding [...] Read More
Can inflamed AD skin become a gateway for topical biologics?➜ DOI: 10.34133/bmr.0368Why it matters:A thermosensitive hyaluronic acid/Pluronic hydrogel delivered mesenchymal stromal cell-derived extracellular vesicles through AD-like lesional skin in mice, improving dermatitis scores, epidermal thickening, mast-cell infiltration, cytokine expression, barrier markers, and oxidative stress.Context and caution:The most intriguing point is that damaged AD skin allowed EV [...] Read More
Fast runners or long-distance champions? Rethinking AD therapy trajectories➜ DOI: 10.1111/all.70395A new Allergy editorial proposes an athletic metaphor for AD therapies: JAK inhibitors as “sprinters,” IL-4/IL-13 biologics as “mid-distance runners,” and emerging immune-resetting approaches as “marathoners.” An attractive framework—but perhaps the key question is not only how therapies run, but how disease evolves in each patient. [...] Read More
AI-Powered Atopic Dermatitis Assessment: Patients Can Contribute + Small punch biopsies and non-negative matrix factorization (NMF) to study AD transcriptome + An important role of IL-22 in Th2 driven acute AD in epidermal reconstructs models + Health-Related Quality of Life in AD and Psoriasis: Are There Distinct Psychological Traits? + Towards a scientific approach of traditional Chinese medicine formulas
Read MoreAI-Powered Atopic Dermatitis Assessment: Patients Can Contribute + Small punch biopsies and non-negative matrix factorization (NMF) to study AD transcriptome + An important role of IL-22 in Th2 driven acute AD in epidermal reconstructs models + Health-Related Quality of Life in AD and Psoriasis: Are There Distinct Psychological Traits? + Towards a scientific approach of traditional Chinese medicine formulas
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Congratulations to Erere OTROFANOWEI and colleagues for this important multi-country study on the accessibility and affordability of emollients for atopic dermatitis in Africa, now published in Journal of Investigative Dermatology. Their survey across 16 mostly Sub-Saharan African countries highlights a crucial but often overlooked reality: even basic moisturizers—the foundation of atopic dermatitis management—remain financially out […]
Read MoreAI-Powered Atopic Dermatitis Assessment: Patients Can Contribute + Small punch biopsies and non-negative matrix factorization (NMF) to study AD transcriptome + An important role of IL-22 in Th2 driven acute AD in epidermal reconstructs models + Health-Related Quality of Life in AD and Psoriasis: Are There Distinct Psychological Traits? + Towards a scientific approach of traditional Chinese medicine formulas
Read MoreAI-Powered Atopic Dermatitis Assessment: Patients Can Contribute + Small punch biopsies and non-negative matrix factorization (NMF) to study AD transcriptome + An important role of IL-22 in Th2 driven acute AD in epidermal reconstructs models + Health-Related Quality of Life in AD and Psoriasis: Are There Distinct Psychological Traits? + Towards a scientific approach of traditional Chinese medicine formulas
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One Th2 Response, Two Outcomes: Itch Versus Inflammation?➜ DOI: 10.1111/exd.70171This research letter suggests that pruritus and inflammation may be driven by partially distinct Th2 programs. In mouse models of dermatitis, IL-31 is mainly produced by a specific subset of T cells, whereas IL-5 and IL-13 are largely derived from ILC2s. This cellular dissociation offers a plausible [...] Read More
AI-Powered Atopic Dermatitis Assessment: Patients Can Contribute + Small punch biopsies and non-negative matrix factorization (NMF) to study AD transcriptome + An important role of IL-22 in Th2 driven acute AD in epidermal reconstructs models + Health-Related Quality of Life in AD and Psoriasis: Are There Distinct Psychological Traits? + Towards a scientific approach of traditional Chinese medicine formulas
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