Federica Casetti, Cristina Has➜ First published: 03 March 2024 - DOI: 10.1111/ddg.15358Dupilumab improves congenital ichthyosis in the context of a filaggrin pathogenic variant. This report from Germany confirms other reports of a response of rare ichthyotic conditions such as Netherton’s syndrome and trichothiodystrophy to targeting IL-4Rα, and that the common FLG mutations may accentuate the inflammatory phenotype [...] Read More
